INTERVENSI ANEMIA DEFISIENSI ZAT BESI PADA IBU HAMIL: A LITERATURE REVIEW
Abstract
Pregnant women are a vulnerable group to anaemia during pregnancy. It happens because the need for iron during pregnancy increases significantly. These conditions would harm both the mother and the fetus. The prevalence of anaemia in pregnancy is high, including in Indonesia. However, comprehensive literature analysis on interventions to address the anaemia of pregnancy is limited. This literature review aims to identify interventions to treat anaemia in pregnancy from various updated sources. This literature review used CINAHL, PubMed, Science Direct, and Google Scholar databases. The keywords used were pregnancy, pregnant women, anaemia, iron deficiency, and interventions. Article criteria included full text, abstract, and title appropriate to the topic. The total number of articles analyzed based on search results are 22 articles. Most research locations are in developing countries, but none in Indonesia. Interventions to treat the anaemia of pregnancy include administering Fe tablets, Fe tablets and additives, fish oil, CSB Plus, Vitamin D, and Vitamin D3. Intervention using Fe, either alone or in combination, was effective in treating anaemia in pregnancy, although there are pregnant women who experience digestive side effects. Applying several interventions to deal with anaemia in pregnancy Intervention research on anaemia in pregnancy can be used in Indonesia.
Keywords
Full Text:
PDFReferences
Abdel Moety, G. A. F., Ali, A. M., Fouad, R., Ramadan, W., Belal, D. S., & Haggag, H. M. (2017). Amino acid chelated iron versus an iron salt in the treatment of iron deficiency anemia with pregnancy: A randomized controlled study. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, 242–246. https://doi.org/10.1016/j.ejogrb.2017.01.003
Ali, M. K., Abbas, A. M., Abdelmagied, A. M., Mohammed, G. E., & Abdalmageed, O. S. (2017). A randomized clinical trial of the efficacy of single versus double-daily dose of oral iron for prevention of iron deficiency anemia in women with twin gestations. Journal of Maternal-Fetal and Neonatal Medicine, 30(23), 2884–2889. https://doi.org/10.1080/14767058.2016.1266478
Bah, A., Muhammad, A. K., Wegmuller, R., Verhoef, H., Goheen, M. M., Sanyang, S., … Prentice, A. M. (2019). Hepcidin-guided screen-and-treat interventions against iron-deficiency anaemia in pregnancy: a randomised controlled trial in The Gambia. The Lancet Global Health, 7(11), e1564–e1574. https://doi.org/10.1016/S2214-109X(19)30393-6
Bhavi, S. B., & Jaju, P. B. (2017). Intravenous iron sucrose v/s oral ferrous fumarate for treatment of anemia in pregnancy. A randomized controlled trial. BMC Pregnancy and Childbirth, 17(1), 1–6. https://doi.org/10.1186/s12884-017-1313-9
Braithwaite, V. S., Crozier, S. R., D’angelo, S., Prentice, A., Cooper, C., Harvey, N. C., … Schoenmakers, I. (2019). The effect of vitamin D supplementation on hepcidin, iron status, and inflammation in pregnant women in the United Kingdom. Nutrients, 11(1). https://doi.org/10.3390/nu11010190
Breymann, C., Milman, N., Mezzacasa, A., Bernard, R., & Dudenhausen, J. (2017). Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: An international, open-label, randomized controlled trial (FER-ASAP). Journal of Perinatal Medicine, 45(4), 443–453. https://doi.org/10.1515/jpm-2016-0050
Darwish, A. M., Khalifa, E. E., Rashad, E., & Farghally, E. (2019). Total dose iron dextran infusion versus oral iron for treating iron deficiency anemia in pregnant women: a randomized controlled trial. Journal of Maternal-Fetal and Neonatal Medicine, 32(3), 398–403. https://doi.org/10.1080/14767058.2017.1379988
Diaz-Castro, J., Moreno-Fernández, J., Hijano, S., Kajarabille, N., Pulido-Moran, M., Latunde-Dada, G. O., … Ochoa, J. J. (2015). DHA supplementation: A nutritional strategy to improve prenatal Fe homeostasis and prevent birth outcomes related with Fe-deficiency. Journal of Functional Foods, 19, 385–393. https://doi.org/10.1016/j.jff.2015.09.051
Goonewardene, I. M. R., & Senadheera, D. I. (2018). Randomized control trial comparing effectiveness of weekly versus daily antenatal oral iron supplementation in preventing anemia during pregnancy. Journal of Obstetrics and Gynaecology Research, 44(3), 417–424. https://doi.org/10.1111/jog.13546
Janmohamed, A., Karakochuk, C. D., Boungnasiri, S., Chapman, G. E., Janssen, P. A., Brant, R., … McLean, J. (2016). Prenatal supplementation with Corn Soya Blend Plus reduces the risk of maternal anemia in late gestation and lowers the rate of preterm birth but does not significantly improve maternal weight gain and birth anthropometric measurements in rural Cambodian women: A randomized trial. American Journal of Clinical Nutrition, 103(2), 559–566. https://doi.org/10.3945/ajcn.114.104034
Jose, A., Mahey, R., Sharma, J. B., Bhatla, N., Saxena, R., Kalaivani, M., & Kriplani, A. (2019). Comparison of ferric Carboxymaltose and iron sucrose complex for treatment of iron deficiency anemia in pregnancy- randomised controlled trial. BMC Pregnancy and Childbirth, 19(1), 1–8. https://doi.org/10.1186/s12884-019-2200-3
Kadir, S. (2019). Faktor Penyebab Anemia Defisiensi Besi Pada Ibu Hamil Di Wilayah Kerja Puskesmas Bongo Nol Kabupaten Boalemo. Jambura Journal of Health Sciences and Research, 1(2), 54–63. https://doi.org/10.35971/jjhsr.v1i2.2396
Kemenkes RI. (2018). Riset Kesehatan Dasar; RISKESDAS. Jakarta: Balitbang Kemenkes RI.
Naqash, A., Ara, R., & Bader, G. N. (2018). Effectiveness and safety of ferric carboxymaltose compared to iron sucrose in women with iron deficiency anemia: phase IV clinical trials. BMC Women’s Health, 18(1), 6. https://doi.org/10.1186/s12905-017-0506-8
Neogi, S. B., Devasenapathy, N., Singh, R., Bhushan, H., Shah, D., Divakar, H., … Baswal, D. (2019). Safety and effectiveness of intravenous iron sucrose versus standard oral iron therapy in pregnant women with moderate-to-severe anaemia in India: a multicentre, open-label, phase 3, randomised, controlled trial. The Lancet Global Health, 7(12), e1706–e1716. https://doi.org/10.1016/S2214-109X(19)30427-9
Nguyen, P. H., Young, M., Gonzalez-Casanova, I., Pham, H. Q., Nguyen, H., Truong, T. V., … Ramakrishnan, U. (2016). Impact of preconception micronutrient supplementation on anemia and iron status during pregnancy and postpartum: A randomized controlled trial in Rural Vietnam. PLoS ONE, 11(12), 1–16. https://doi.org/10.1371/journal.pone.0167416
Parisi, F., Berti, C., Mandò, C., Martinelli, A., Mazzali, C., & Cetin, I. (2017). Effects of different regimens of iron prophylaxis on maternal iron status and pregnancy outcome: a randomized control trial. Journal of Maternal-Fetal and Neonatal Medicine, 30(15), 1787–1792. https://doi.org/10.1080/14767058.2016.1224841
Rezk, M., Dawood, R., Abo-Elnasr, M., Al Halaby, A., & Marawan, H. (2016). Lactoferrin versus ferrous sulphate for the treatment of iron deficiency anemia during pregnancy: A randomized clinical trial. Journal of Maternal-Fetal and Neonatal Medicine, 29(9), 1387–1390. https://doi.org/10.3109/14767058.2015.1049149
Romauli. (2011). Konsep Dasar Asuhan Kebidanan I: Konsep Dasar Asuhan Kehamilan. Yogyakarta: Nuha Medika.
Rosda, R. (2019). FAKTOR-FAKTOR RESIKO KEJADIAN ANEMIA PADA IBU HAMIL DI WILAYAH KERJA PUSKESMAS KEBUN KOPI JAMBI TAHUN 2018. Jurnal Ilmu-Ilmu Kesehatan, (Vol 5, No 1 (2019): Jurnal Ilmu-Ilmu Kesehatan), 14. Retrieved from http://ojs.akpergapu-jambi.ac.id/index.php/OjsGapu/article/view/28/Vol.5%2C No.1 2019
Sanchez-Gonzalez, L. R., Castro-Melendez, S. E., Angeles-Torres, A. C., Castro-Cortina, N., Escobar-Valencia, A., & Quiroga-Garza, A. (2016). Efficacy and safety of adjuvant recombinant human erythropoietin and ferrous sulfate as treatment for iron deficiency anemia during the third trimester of pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 205, 32–36. https://doi.org/10.1016/j.ejogrb.2016.08.004
Shinar, S., Skornick-Rapaport, A., & Maslovitz, S. (2017). Iron supplementation in singleton pregnancy: Is there a benefit to doubling the dose of elemental iron in iron-deficient pregnant women? a randomized controlled trial. Journal of Perinatology, 37(7), 782–786. https://doi.org/10.1038/jp.2017.43
Shinar, Shiri, Skornick-Rapaport, A., & Maslovitz, S. (2017). Iron Supplementation in Twin Pregnancy - The Benefit of Doubling the Iron Dose in Iron Deficient Pregnant Women: A Randomized Controlled Trial. Twin Research and Human Genetics, 20(5), 419–424. https://doi.org/10.1017/thg.2017.43
Tabrizi, J. S., Asghari, A., Pourali, F., Kousha, H., & Nikniaz, L. (2019). Effects of Food Supplementation During Pregnancy on Maternal Weight Gain, Hemoglobin Levels and Pregnancy Outcomes in Iran. Maternal and Child Health Journal, 23(2), 258–264. https://doi.org/10.1007/s10995-018-2648-1
Vahedi, L., Ostadrahimi, A., Edalati-Fard, F., Aslani, H., & Farshbaf-Khalili, A. (2018). Is fish oil supplementation effective on maternal serum FBS, oral glucose tolerance test, hemoglobin and hematocrit in low risk pregnant women? A triple-blind randomized controlled trial. Journal of Complementary and Integrative Medicine, 15(3), 1–9. https://doi.org/10.1515/jcim-2018-0010
Waryana. (2010). Nutrisi Janin dan Ibu Hamil. Yogyakarta: Nuha Medika.
Zhao, G., Xu, G., Zhou, M., Jiang, Y., Richards, B., Clark, K. M., … Lozoff, B. (2015). Prenatal iron supplementation reduces maternal anemia, iron deficiency, and iron deficiency anemia in a randomized clinical trial in rural China, but iron deficiency remains widespread in mothers and neonates. Journal of Nutrition, 145(8), 1916–1923. https://doi.org/10.3945/jn.114.208678
DOI: https://doi.org/10.36780/jmcrh.v5i2.259
Refbacks
- There are currently no refbacks.
Copyright (c) 2023 Journal of Maternity Care and Reproductive Health
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
This Journal is indexed on:
Redaksi Journal of Maternity Care and Reproductive Health:
Fakultas Keperawatan, Universitas Padjadjaran
Jalan Raya Bandung-Sumedang Km. 21 Jatinangor, Sumedang, Indonesia 45363
WA: 081321793280
Email: admin@mcrhjournal.or..id
JMCRH is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
http://www.statistics.mcrhjournal.or.id